{"doc_desc":{"title":"Association between long-term occupational exposure to PM10 and allergic diseases in subway workers","producers":[{"name":"Center for Primary Care and Public Health (Unisant\u00e9), University of Lausanne, Switzerland","abbreviation":"Unisant\u00e9","affiliation":"","role":"Data publisher"}]},"study_desc":{"title_statement":{"idno":"10.16909-DATASET-47","title":"Association between long-term occupational exposure to PM10 and allergic diseases in subway workers"},"authoring_entity":[{"name":"GUSEVA CANU, Irina","affiliation":"Center for Primary Care and Public Health (Unisant\u00e9), Department of occupational and environmental health (DSTE)"}],"production_statement":{"producers":[{"name":"FREUND, Romain","affiliation":"Center for Primary Care and Public Health (Unisant\u00e9), Department of occupational and environmental health (DSTE)","role":"researcher and co-author"},{"name":"SAUVAIN, Jean-Jacques","affiliation":"Center for Primary Care and Public Health (Unisant\u00e9), Department of occupational and environmental health (DSTE)","role":"co-author"},{"name":"SUAREZ, Guillaume","affiliation":"Center for Primary Care and Public Health (Unisant\u00e9), Department of occupational and environmental health (DSTE)","role":"co-author"},{"name":"WILD, Pascal","affiliation":"Center for Primary Care and Public Health (Unisant\u00e9), Department of occupational and environmental health (DSTE)","role":"co-author"},{"name":"CHARREAU, Thomas","affiliation":"Center for Primary Care and Public Health (Unisant\u00e9), Department of occupational and environmental health (DSTE)","role":"co-author"},{"name":"PRALONG, Jacques A","affiliation":"Faculty of Medicine, University of Geneva SwissMedPro Health Services  H\u00f4pital de la Tour, Geneva","role":"co-author"},{"name":"DEBATISSE, Amelie","affiliation":"Autonomous Paris Transport Authority (RATP), Paris, France","role":"co-author"},{"name":"JOUANNIQUE, Val\u00e9rie","affiliation":"Autonomous Paris Transport Authority (RATP), Paris, France","role":"co-author"},{"name":"SAKTHITHASAN, Kirushanti","affiliation":"Autonomous Paris Transport Authority (RATP), Paris, France","role":"co-author"}],"copyright":"(c) 2024, Center for Primary Care and Public Health (Unisant\u00e9), University of Lausanne, Switzerland","funding_agencies":[{"name":"Swiss National Science Foundation","abbreviation":"SNSF","role":"Grant N\u25e6 IZCOZ0_177067"}],"grant_no":"Grant N\u25e6 IZCOZ0_177067"},"version_statement":{"version_date":""},"study_info":{"keywords":[{"keyword":"Asthma","vocab":"","uri":""},{"keyword":"Atopy","vocab":"","uri":""},{"keyword":"Exhaled breath condensate","vocab":"","uri":""},{"keyword":"Nitrite","vocab":"","uri":""},{"keyword":"PM10 exposure","vocab":"","uri":""}],"abstract":"Background: Long-term exposure to ambient particulate matter (PM) in adults increases the risk of allergic diseases exacerbation. We evaluated whether a long-term occupational exposure to subway PM10 is associated with the prevalence of atopic sensitization and allergic diseases (i.e., current asthma, current rhinitis or current eczema) and whether the latter are associated with biomarkers measured in exhaled breath condensate (EBC) of subway workers.\n\nMethods: Participants were randomly selected from a 15,000-subway worker cohort. Individual inhaled PM10 mass (iPM10) per shift at work was estimated using a company-specific job-exposure-matrix based on PM10 measurements conducted between 2004 and 2019. iPM10 was modelled as function of PM10 exposure averaged over the participant\u2019s employment in the Parisian subway, inhalation rate, and filtration efficiency of the respiratory protection used. Atopic sensitization was tested using skin prick tests. Allergic diseases were assessed using self-administered questionnaire. Associations were assessed using multivariable logistic regression models adjusted for potential confounders. \n\nResults: Amongst 287 participants, 39% had an atopic sensitization, 25% a poly-atopic sensitization, 5","coll_dates":[{"start":"2004\/01\/01","end":"2019\/12\/31","cycle":""}],"nation":[{"name":"Switzerland","abbreviation":"CHE"},{"name":"France","abbreviation":"FR"}],"analysis_unit":"The unit of analysis is the individual. The number of participants is 287.","data_kind":"This repository is meant to share additional material for the article.\n\t\t  \n\t\t  All data and biological samples were collected from March through May 2021 according to the study protocol (Guseva Canu I, Hemmendinger M, Sauvain JJ, Suarez G, Hopf NB, Pralong JA, et al. Respiratory Disease Occupational Biomonitoring Collaborative Project (ROBoCoP): A longitudinal pilot study and implementation research in the Parisian transport company. J Occup Med Toxicol. 2021;16(1):22.). The data can not be shared."},"method":{"data_collection":{"coll_mode":"Other [oth]"}},"data_access":{"dataset_use":{"contact":[{"name":"Documentation and data Unit","affiliation":"Center for Primary Care and Public Health (Unisant\u00e9), University of Lausanne, Switzerland","email":"udd.data@unisante.ch","uri":""}],"cit_req":"Freund R, Sauvain JJ, Suarez G, Wild P, Charreau T, Pralong J, Debatisse A, Jouannique V, Sakthithasan K, Guseva Canu I. Association between long-term occupational exposure to PM10 and allergic diseases in subway workers. Center for Primary Care and Public Health (Unisant\u00e9), University of Lausanne, Switzerland. Version 1.0 of the related material (03\/2024), provided by the Unisant\u00e9 Research Data Repository. DOI:https:\/\/doi.org\/10.16909\/dataset\/47","conditions":"The data are not available. Only related material is shared throught the repository"}}},"schematype":"survey"}