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<codeBook version="1.2.2" ID="10.16909-dataset-61" xml-lang="en" xmlns="http://www.icpsr.umich.edu/DDI" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.icpsr.umich.edu/DDI http://www.icpsr.umich.edu/DDI/Version1-2-2.xsd">
  <docDscr>
    <citation>
      <titlStmt>
         <titl>
          Serum dioxin concentrations in the Lausanne population – A pilot population-based survey
        </titl>
        <subTitl>
          
        </subTitl>
        <altTitl>
          
        </altTitl>
        <parTitl>
          Etude d’imprégnation de la population lausannoise aux dioxines – Etude pilote basée sur la population
        </parTitl>
        <IDNo>
          10.16909-dataset-61
        </IDNo>
      </titlStmt>
      <prodStmt>
        <software version="1.2" date="2011-01-07">
          Metadata Editor
        </software>
      </prodStmt>
      <distStmt>
        
      </distStmt>
    </citation>
    <guide>
      <![CDATA[ ]]>
    </guide>
    <notes>
      <![CDATA[ ]]>
    </notes>
  </docDscr>
  <stdyDscr>
    <citation>
      <titlStmt>
        <titl>
          Serum dioxin concentrations in the Lausanne population – A pilot population-based survey
        </titl>
        <subTitl>
          
        </subTitl>
        <altTitl>
          
        </altTitl>
        <parTitl>
          Etude d’imprégnation de la population lausannoise aux dioxines – Etude pilote basée sur la population
        </parTitl>
        <IDNo>
          10.16909-dataset-61
        </IDNo>
      </titlStmt>
      <rspStmt>
        <AuthEnty affiliation="Unisanté, Center for Primary Care and Public Health &amp; University of Lausanne, Lausanne, Switzerland ">David Vernez</AuthEnty>
<AuthEnty affiliation="Unisanté, Center for Primary Care and Public Health &amp; University of Lausanne, Lausanne, Switzerland ">Aurélie Berthet</AuthEnty>

        <othId affiliation="Unisanté, Center for Primary Care and Public Health &amp; University of Lausanne, Lausanne, Switzerland " role="Study nurse">
<p>Agathe Deschamps</p>
</othId>

      </rspStmt>
      <prodStmt>
        <producer abbr="CO" affiliation="Unisanté, Center for Primary Care and Public Health &amp; University of Lausanne, Lausanne, Switzerland" role="Co-author, researcher">Oltramare Christelle</producer>
<producer abbr="MZ" affiliation="EMPA" role="Co-author, researcher">Markus Zennegg</producer>
<producer abbr="MB" affiliation="Unisanté, Center for Primary Care and Public Health &amp; University of Lausanne, Lausanne, Switzerland " role="Co-author, researcher">Murielle Bochud</producer>
<producer abbr="VR" affiliation="Unisanté, Center for Primary Care and Public Health &amp; University of Lausanne, Lausanne, Switzerland " role="Co-author, researcher">Valentin Rousson</producer>
<producer abbr="JR" affiliation="Unisanté, Center for Primary Care and Public Health &amp; University of Lausanne, Lausanne, Switzerland " role="Co-author, researcher">Julien Riou</producer>
<producer abbr="HY" affiliation="Unisanté, Center for Primary Care and Public Health &amp; University of Lausanne, Lausanne, Switzerland " role="Co-author, researcher">Yves Henchoz</producer>

        <copyright>
          (c) 2026, Unisanté, Center for Primary Care and Public Health &amp; University of Lausanne, Lausanne, Switzerland 
        </copyright>
        <software version="1.2" date="2011-01-07">
          Metadata Editor
        </software>
        <fundAg abbr="DGS" role="">Department of Health, Canton of Vaud </fundAg>
<grantNo agency="Department of Health, Canton of Vaud " role="">OMC/2022/011</grantNo>

      </prodStmt>
      <distStmt>
        <contact affiliation="DSTE, Unisanté, Center for Primary Care and Public Health &amp; University of Lausanne, Lausanne, Switzerland " email="david.vernez@unisante.ch" URI="">David Vernez</contact>
<contact affiliation="DSTE, Unisanté, Center for Primary Care and Public Health &amp; University of Lausanne, Lausanne, Switzerland " email="aurélie.berthet@unisante.ch" URI="">Aurélie Berthet</contact>
<contact affiliation="DSTE, Unisanté, Center for Primary Care and Public Health &amp; University of Lausanne, Lausanne, Switzerland " email="christelle.oltramare@unisante.ch" URI="">Christelle Oltramare</contact>

      </distStmt>
      <serStmt>
        <serName>
          
        </serName>
        <serInfo>
          <![CDATA[]]>
        </serInfo>
      </serStmt>
      <verStmt>
        <version date=" ">
          <![CDATA[]]>
        </version>
        <verResp affiliation=" "/>
        <notes>
          <![CDATA[]]>
        </notes>
      </verStmt>
    </citation>
    <stdyInfo>
      <subject>
        <keyword>Environmental Exposure</keyword>
		<keyword>Dioxins</keyword>
		<keyword>PCDD/Fs</keyword>
		<keyword>Food frequency questionnaire</keyword>
		<keyword>Environmental contamination</keyword>
      </subject>
      <abstract>
        <![CDATA[
		Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) are ubiquitous in the environment and the main route of exposure for humans is food. A high and widespread soil contamination was discovered in 2021 in Lausanne city. Previous human exposure assessment study showed that consumption of home-produced eggs and cucurbits were dominant exposure scenarios. In the absence of epidemiological data in Switzerland, we conducted a cross-sectional study in 2023 to assess the difference between control (n=50) and exposed (n=51) groups, living in the contaminated area and reporting to consume selected home-produced foods (eggs and cucurbits). We sampled blood serum and asked the participants to fill several questionnaires on their lifestyle and dietary habits.
		
		Primary objective: Assess exposure to PCDD/Fs from dietary intake of foods produced in contaminated areas of Lausanne
Secondary objective: Correlate serum concentrations of endocrine disruptors with the Aryl hydrocarbon receptor (AhR) response
Third objective: Determine the exposure determinants influencing the serum concentrations of PCDD/Fs and OCPs
]]>
      </abstract>
      <sumDscr>
        <collDate date="2023-05-01" event="start" cycle="1" />
<collDate date="2023-09-15" event="end" cycle="1" />

        
        <nation abbr="CHE">Switzerland</nation>

        <geogCover>
          <![CDATA[This study focused on the soil contamination of Lausanne, selecting healthy volunteers from Lausanne and surrounding areas. ]]>
        </geogCover>
        <anlyUnit>
          <![CDATA[Individuals]]>
        </anlyUnit>
        <universe>
          <![CDATA[]]>
        </universe>
        <dataKind>
          Survey data, Face to face medical visit
        </dataKind>
      </sumDscr>
      <notes>
        <![CDATA[]]>
      </notes>
    </stdyInfo>
    <method>
      <dataColl>
        
        <sampProc>
          <![CDATA[Sample size =102]]>
        </sampProc>
        <deviat>
          <![CDATA[]]>
        </deviat>
        <collMode>
          Internet [int]
        </collMode>
        <resInstru>
          <![CDATA[Online questionnaire]]>
        </resInstru>
        <sources/>
        <collSitu>
          <![CDATA[]]>
        </collSitu>
        <actMin>
          <![CDATA[]]>
        </actMin>
        <weight>
          <![CDATA[]]>
        </weight>
        <cleanOps>
          <![CDATA[]]>
        </cleanOps>
      </dataColl>
      <notes>
        <![CDATA[]]>
      </notes>
      <anlyInfo>
        <respRate>
          <![CDATA[]]>
        </respRate>
        <EstSmpErr>
          <![CDATA[]]>
        </EstSmpErr>
        <dataAppr>
          <![CDATA[]]>
        </dataAppr>
      </anlyInfo>
    </method>
    <dataAccs>
		<setAvail>
		<accsPlac URI="https://doi.org/10.16909/61">
	Unisanté Data repository
		</accsPlac>
		<avlStatus>
	The dataset is available on request for research purpose only.
To get access to data, the following procedure must be followed:
· Create an account (Login → Register)
· Go to the Data Catalog and click on the study of interest (https://doi.org/10.16909/dataset/61)
· Once on the study page, click on the tab "Data Access"
· Fill in the application form and submit
· The request will then be reviewed by Unisanté. If accepted, a Data transfer agreement will be created
· Sign the Data transfert agreement
Important: Before submitting a request, please check whether the data is at all useful for your project. The codebooks with the corresponding information are filed under Documentation and do not require registration.
		</avlStatus>
		</setAvail>

      <useStmt>
        
        <contact affiliation="Unisanté, University Center for Primary Care and Public Health, Lausanne, Switzerland" email="udd.data@unisante.ch" URI="https://www.unisante.ch/fr/formation-recherche/bibliotheque">Documentation and data unit (UDD)</contact>

        <citReq>
          <![CDATA[Vernez, D., Berthet, A., Oltramare, C., Zennegg, M., Bochud, M., Rousson, V., Riou, J., & Henchoz, Y. Serum dioxin concentrations in the Lausanne population – A pilot population-based survey. Unisanté, Center for Primary Care and Public Health &amp; University of Lausanne, Lausanne, Switzerland. Version 1.0 of the licensed dataset (02/2026), provided by the Unisanté Research Data Repository. DOI:https://doi.org/10.16909/dataset/61]]>
        </citReq>
        <conditions>
          <![CDATA[This dataset is submitted to the Federal Act on Research involving Human Beings (HRA). Therefore, an ethical approval will be required to use this dataset.
		  The Data transfer agreement must be signed before releasing the dataset]]>
        </conditions>
        <disclaimer>
          <![CDATA[]]>
        </disclaimer>
      </useStmt>
    </dataAccs>
  </stdyDscr>
  <dataDscr/>
</codeBook>
