{"doc_desc":{"title":"Serum dioxin concentrations in the Lausanne population \u2013 A pilot population-based survey","idno":"10.16909-dataset-61"},"study_desc":{"title_statement":{"idno":"10.16909-dataset-61","title":"Serum dioxin concentrations in the Lausanne population \u2013 A pilot population-based survey","translated_title":"Etude d\u2019impr\u00e9gnation de la population lausannoise aux dioxines \u2013 Etude pilote bas\u00e9e sur la population"},"authoring_entity":[{"name":"David Vernez","affiliation":"Unisant\u00e9, Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland "},{"name":"Aur\u00e9lie Berthet","affiliation":"Unisant\u00e9, Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland "}],"oth_id":[{"name":"Agathe Deschamps","affiliation":"Unisant\u00e9, Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland ","email":"","role":"Study nurse"}],"production_statement":{"producers":[{"name":"Oltramare Christelle","abbr":"CO","affiliation":"Unisant\u00e9, Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland","role":"Co-author, researcher"},{"name":"Markus Zennegg","abbr":"MZ","affiliation":"EMPA","role":"Co-author, researcher"},{"name":"Murielle Bochud","abbr":"MB","affiliation":"Unisant\u00e9, Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland ","role":"Co-author, researcher"},{"name":"Valentin Rousson","abbr":"VR","affiliation":"Unisant\u00e9, Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland ","role":"Co-author, researcher"},{"name":"Julien Riou","abbr":"JR","affiliation":"Unisant\u00e9, Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland ","role":"Co-author, researcher"},{"name":"Yves Henchoz","abbr":"HY","affiliation":"Unisant\u00e9, Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland ","role":"Co-author, researcher"}],"copyright":"(c) 2026, Unisant\u00e9, Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland","funding_agencies":[{"name":"Department of Health, Canton of Vaud","abbr":"DGS","role":""}],"grant_no":"OMC\/2022\/011"},"distribution_statement":{"contact":[{"name":"David Vernez","affiliation":"DSTE, Unisant\u00e9, Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland ","email":"david.vernez@unisante.ch","uri":""},{"name":"Aur\u00e9lie Berthet","affiliation":"DSTE, Unisant\u00e9, Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland ","email":"aur\u00e9lie.berthet@unisante.ch","uri":""},{"name":"Christelle Oltramare","affiliation":"DSTE, Unisant\u00e9, Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland ","email":"christelle.oltramare@unisante.ch","uri":""}]},"version_statement":{"version_date":" "},"study_info":{"keywords":[{"keyword":"Environmental Exposure","vocab":"","uri":""},{"keyword":"Dioxins","vocab":"","uri":""},{"keyword":"PCDD\/Fs","vocab":"","uri":""},{"keyword":"Food frequency questionnaire","vocab":"","uri":""},{"keyword":"Environmental contamination","vocab":"","uri":""}],"abstract":"Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD\/Fs) are ubiquitous in the environment and the main route of exposure for humans is food. A high and widespread soil contamination was discovered in 2021 in Lausanne city. Previous human exposure assessment study showed that consumption of home-produced eggs and cucurbits were dominant exposure scenarios. In the absence of epidemiological data in Switzerland, we conducted a cross-sectional study in 2023 to assess the difference between control (n=50) and exposed (n=51) groups, living in the contaminated area and reporting to consume selected home-produced foods (eggs and cucurbits). We sampled blood serum and asked the participants to fill several questionnaires on their lifestyle and dietary habits.\n\t\t\n\t\tPrimary objective: Assess exposure to PCDD\/Fs from dietary intake of foods produced in contaminated areas of Lausanne\nSecondary objective: Correlate serum concentrations of endocrine disruptors with the Aryl hydrocarbon receptor (AhR) response\nThird objective: Determine the exposure determinants influencing the serum concentrations of PCDD\/Fs and OCPs","coll_dates":[{"start":"2023-05-01","end":"2023-09-15","cycle":"1"}],"nation":[{"name":"Switzerland","abbreviation":"CHE"}],"geog_coverage":"This study focused on the soil contamination of Lausanne, selecting healthy volunteers from Lausanne and surrounding areas.","analysis_unit":"Individuals","data_kind":"Survey data, Face to face medical visit"},"method":{"data_collection":{"sampling_procedure":"Sample size =102","coll_mode":["Internet [int]"],"research_instrument":"Online questionnaire","sources":[{"name":"","origin":"","characteristics":""}]}},"data_access":{"dataset_availability":{"access_place":"Unisant\u00e9 Data repository","access_place_url":"https:\/\/doi.org\/10.16909\/61","status":"The dataset is available on request for research purpose only.\nTo get access to data, the following procedure must be followed:\n\u00b7 Create an account (Login \u2192 Register)\n\u00b7 Go to the Data Catalog and click on the study of interest (https:\/\/doi.org\/10.16909\/dataset\/61)\n\u00b7 Once on the study page, click on the tab \"Data Access\"\n\u00b7 Fill in the application form and submit\n\u00b7 The request will then be reviewed by Unisant\u00e9. If accepted, a Data transfer agreement will be created\n\u00b7 Sign the Data transfert agreement\nImportant: Before submitting a request, please check whether the data is at all useful for your project. The codebooks with the corresponding information are filed under Documentation and do not require registration."},"dataset_use":{"contact":[{"name":"Documentation and data unit (UDD)","affiliation":"Unisant\u00e9, University Center for Primary Care and Public Health, Lausanne, Switzerland","email":"udd.data@unisante.ch","uri":"https:\/\/www.unisante.ch\/fr\/formation-recherche\/bibliotheque"}],"cit_req":"Vernez, D., Berthet, A., Oltramare, C., Zennegg, M., Bochud, M., Rousson, V., Riou, J., & Henchoz, Y. Serum dioxin concentrations in the Lausanne population \u2013 A pilot population-based survey. Unisant\u00e9, Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland. Version 1.0 of the licensed dataset (02\/2026), provided by the Unisant\u00e9 Research Data Repository. DOI:https:\/\/doi.org\/10.16909\/dataset\/61","conditions":"This dataset is submitted to the Federal Act on Research involving Human Beings (HRA). Therefore, an ethical approval will be required to use this dataset.\n\t\t  The Data transfer agreement must be signed before releasing the dataset"}}},"schematype":"survey","tags":[{"tag":"Adults"},{"tag":"Dioxins"},{"tag":"Environmental-contamination"},{"tag":"Food-frequency-questionnaire"},{"tag":"Humans"},{"tag":"PCDDFs"}]}